The Devil's Nest itself seems to be connected to a series of maze-like underground escape routes, mostly ending in the large sewer network below.
Shortly after Edward Elric and Izumi Curtis travel into the pub in search of a captured Alphonse, the place is raided by King Bradley and his military forces. The ultimate fate of The Devil's Nest after this attack is unknown.
- In the 2003 anime, Frank Archer, a character exclusive to that series, leads the raid on the Devil's Nest rather than King Bradley, causing the chimera's roles to be extended, particularly Martel's.
- During the fight between Ed and Greed, in one of the frames, a bottle of liquor labeled Stray Dog can be seen. This is a reference to Hiromu Arakawa's earlier manga series of the same name.