- The character of Al bears some resemblance to Agilulf, the protagonist of Italo Calvino's The Nonexistent Knight. Like Al, Agilulf is nothing but a living suit of armor, a formidable fighter, and holds a sense of good manners.
- Al was voted the fourth most popular character of the series in the recent fan poll.
- In a manga extra, it is shown that Al only allows women and cats into his armor, though the 2003 Anime depicts him carrying Black Hayate (a dog) inside of him, and in chapter 56 he is also shown carrying Xiao-Mei (a panda) there in, although he believes Xiao-Mei to be a cat.
- Al is one of two people in the series to know that Winry and Ed have romantic feelings for each other, the other being Riza Hawkeye.
- In the manga and 2009 anime, Alphonse, as a direct descendant of Van Hohenheim, is close blood kin to Father and all the seven Homunculi (although King Bradley can be a slight exception, as he is a human based Homunculus, but nevertheless still shares the close blood kin to Al like the others). Additionally, Arakawa has jokingly confirmed that, in the manga, Al (along with Ed) is technically uncle to the seven Homunculi, as he relates to them by blood.
- Al's breech cloth is white in the manga and 2009 anime, while in the 2003 anime, it's light violet.
- In episode 12 of Lucky Star, a cosplayer is seen portraying Alphonse in full armor at Comiket, although the suit of armour has a yellowish tint.
- In an app called "Alchemy", there is an element called "Metal Golem". The Metal Golem looks a lot like Alphonse.
- Al makes a cameo appearance in Episode 5 of the anime series, Hayate the Combat Butler when he is referenced by Nagi Sanzen'in, who shares the same Japanese voice actress as him.
- Alphonse has two theme songs on the Brotherhood anime CD. One of them is called "Kaze ni Dakarete", performed by his seiyu, Rie Kugimiya, and another called "Restore Steppin'", performed by both Kugimiya and Edward's seiyu, Romi Park.
- In the manga and 2003 anime, the rectangular plate under the chin of Alphonse's helmet has five openings. In the 2009 anime, it has four, excluding rare animation mistakes where it is drawn with three or five.
- Originally, Arakawa did not draw Alphonse's armor face as displaying emotions of any kind, regardless of circumstance or emotional climate. It wasn't until Chapter 4: Battle on the Train that he began "making faces" during comedic scenes. (However, both animes employed this gag as early as their first episodes.)
- It is assumed that Al's human height at the end of the series to be 5'10 (177.8cm) and his brother Ed to be of 5'9 (175.26cm)
- His 2003 VA Actor Aaron Disuke who voiced Arslan in Arslan Senki with Edward's voice actor Vic Mignogna playing Himles and they would play brothers in Funimation's redubbing of The Vision of Escaflowne
|Fullmetal Alchemist Characters|
|Eye of God|Truth|
Alexandre | Arzen | Heathcliffe Arbor | Frank Archer | Olivier Mira Armstrong | King Bradley | Heymans Breda | Briggs Doctor | Denny Brosh | Buccaneer | Rebecca Catalina | Charlie | Clemin | Damiano | Darius | Henry Douglas | Edison | Vato Falman | Fessler | Fokker | Kain Fuery | Gamelan | Gardner | Grumman | Hakuro | Harris | Jean Havoc | Riza Hawkeye | Heinkel | Henschel | Maes Hughes | Jerso | Karley | Miles | Raven | Richard | Maria Ross | Sheska | Smith | Storch | Yakovlev | Yoki | Zampano | Gold-Toothed Doctor | Doctor Knox
| Rockbell Family / Rockbell Automail|
| Elric-Hohenheim Family |
| Armstrong Family|